When making cuts to regions on an alternate playlist while playing back the main or alternate playlist, the audio drops out similar to how it sounds when adding an insert.
During playback, editing a clip on a stereo track while in playlist view causes a system-wide playback glitch the first time an edit is made, and then a playhead jump on the second edit. Mono playlist editing doesn’t cause the glitch, but stereo and LCR do. PT 12.8.1 doesn't exhibit this behavior, 12.8.3 does.
Pro Tools 12.8.3